A Study of Ustekinumab or Guselkumab in Pediatric Participants With Active Juvenile Psoriatic Arthritis (PSUMMIT-Jr)
Last Updated May 14, 2025
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CR109101
OVERVIEW
-
Sexes Eligible for Study
all -
Age
years -
Phase
phase 33 -
Sites
Sites -
Status
Recruiting
SUMMARY
The purpose of this study is to evaluate the pharmacokinetics (PK), efficacy, safety and immunogenicity of ustekinumab and guselkumab in active juvenile psoriatic arthritis (jPsA).
CONDITIONS
- Arthritis, Juvenile
ELIGIBILITY
Inclusion Criteria:
* Diagnosis of juvenile psoriatic arthritis (jPsA) by Vancouver criteria with exclusion of enthesitis-related arthritis (ERA). Diagnosis made >=3 months (that is, 90 days) prior to screening
* Active disease in at least greater than or equal to (>=) 3 joints a
DETAILS
LOCATIONS
Locations in:
United States, Argentina, Denmark, France, Germany, Italy, Spain, Türkiye, United Kingdom, Poland
| Country (10) | City or Province (50) | Status |
| United States | Los Angeles Childrens Hospital Los Angeles |
RECRUITING
|
| United States | Los Angeles UCLA |
RECRUITING
|
| United States | Boston Harvard Medical School - Boston Children's Hospital |
RECRUITING
|
| United States | Bronx Montefiore Medical Center |
RECRUITING
|
| United States | New York Northwell Health |
RECRUITING
|
| United States | Chapel Hill University of North Carolina |
RECRUITING
|
| United States | Portland Legacy Emanuel Medical Center |
TERMINATED
|
| United States | Salt Lake City University of Utah |
RECRUITING
|
| Argentina | Ciudad Autonoma Buenos Aires STAT Research S A |
RECRUITING
|
| Argentina | Cordoba Hospital de Ninos de Cordoba |
RECRUITING
|
| Argentina | La Plata Instituto Medico Platense |
RECRUITING
|
| Argentina | Rosario Instituto Caici |
RECRUITING
|
| Argentina | San Miguel De Tucuman Centro Medico Privado de Reumatologia |
RECRUITING
|
| Denmark | Arhus Aarhus Universitetshospital |
RECRUITING
|
| France | Caen CHU de Caen |
RECRUITING
|
| France | Le Kremlin Bicêtre Hopital de Bicetre |
RECRUITING
|
| France | Marseille Hopital Nord Marseille |
RECRUITING
|
| France | Vandoeuvre les Nancy Hôpital D'Enfants |
RECRUITING
|
| Germany | Sankt Augustin Asklepios Klinik Sankt Augustin |
RECRUITING
|
| Italy | Brescia Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia Presidio Spedali Civili |
RECRUITING
|
| Italy | Genova Istituto Giannina Gaslini |
RECRUITING
|
| Italy | Milano Centro Specialistico Ortopedico Traumatologico Gaetano Pini CTO |
RECRUITING
|
| Italy | Milano Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico |
RECRUITING
|
| Spain | Barcelona Hosp Univ Vall D Hebron |
RECRUITING
|
| Spain | Barcelona Hosp. de La Santa Creu I Sant Pau |
RECRUITING
|
| Spain | Cordoba Hosp Reina Sofia |
RECRUITING
|
| Spain | Santiago de Compostela Hosp. Clinico Univ. de Santiago |
RECRUITING
|
| Spain | Valencia Hosp. Univ. I Politecni La Fe |
RECRUITING
|
| Türkiye | Ankara Hacettepe Universitesi Hastanesi |
RECRUITING
|
| Türkiye | Istanbul Istanbul University Cerrahpasa Medical Faculty |
RECRUITING
|
| Türkiye | Istanbul Umraniye Training and Research Hospital |
RECRUITING
|
| United Kingdom | London Great Ormond Street Hospital |
RECRUITING
|
| United Kingdom | Nottingham Nottingham University Hospitals NHS Trust |
RECRUITING
|
| United Kingdom | Sheffield Sheffield Children's Hospital |
RECRUITING
|
| United Kingdom | Southampton Southampton General Hospital |
RECRUITING
|
| United Kingdom | Staffordshire Haywood Hospital |
RECRUITING
|
| Türkiye | Kocaeli Kocaeli University Medical Faculty |
RECRUITING
|
| United Kingdom | Manchester Royal Manchester Children's Hospital |
RECRUITING
|
| United States | Cincinnati Cincinnati Children's Hospital Medical Center |
RECRUITING
|
| Denmark | Odense Odense Universitets Hospital |
COMPLETED
|
| Germany | Berlin Charite Universitatsmedizin Berlin Campus Virchow Klinikum |
RECRUITING
|
| Germany | Hamburg Schon Klinik Hamburg Eilbek |
RECRUITING
|
| Poland | Lodz CSK, Uniwersyteckie Centrum Pediatrii im.M.Konopnickiej |
RECRUITING
|
| Poland | Sosnowiec Centrum Zdrowia Dziecka i Rodziny im Jana Pawla II w Sosnowcu Sp z o o |
RECRUITING
|
| Poland | Warszawa Narodowy Instytut Geriatrii Reumatologii i Rehabilitacji im prof dr hab med Eleonory Reicher |
RECRUITING
|
| Spain | Sevilla Hosp. Infanta Luisa |
COMPLETED
|
| United Kingdom | Newcastle upon Tyne Royal Victoria Infirmary |
COMPLETED
|
| United Kingdom | Stoke on Trent Royal Stoke University Hospital |
RECRUITING
|
| France | Toulouse cedex 9 CHU de Toulouse Hopital des Enfants |
COMPLETED
|
| Italy | Roma IRCCS Ospedale Pediatrico Bambino Gesu |
RECRUITING
|
Geo Locations
34.05223, -118.24368
34.05223, -118.24368
42.35843, -71.05977
40.84985, -73.86641
40.71427, -74.00597
35.9132, -79.05584
45.52345, -122.67621
40.76078, -111.89105
-34.61315, -58.37723
-31.4135, -64.18105
-34.92145, -57.95453
-32.94682, -60.63932
-26.82414, -65.2226
56.15674, 10.21076
49.18585, -0.35912
48.81471, 2.36073
43.29551, 5.38958
48.65, 6.18333
50.77538, 7.197
45.53558, 10.21472
44.40478, 8.94438
45.46427, 9.18951
45.46427, 9.18951
41.38879, 2.15899
41.38879, 2.15899
37.89155, -4.77275
42.88052, -8.54569
39.46975, -0.37739
39.91987, 32.85427
41.01384, 28.94966
41.01384, 28.94966
51.50853, -0.12574
52.9536, -1.15047
53.38297, -1.4659
50.90395, -1.40428
53.056961, -2.1914135
39.62497, 27.51145
53.48095, -2.23743
39.12713, -84.51435
55.39594, 10.38831
52.52437, 13.41053
53.57532, 10.01534
51.75, 19.46667
50.28682, 19.10385
52.22977, 21.01178
37.38283, -5.97317
54.97328, -1.61396
53.00415, -2.18538
43.60426, 1.44367
41.89193, 12.51133
x
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10
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5
Indicates < 10 sites in this region: click to zoom in.
Corresponds to individual site.